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. 2020 May 4;11:45–54. doi: 10.2147/POR.S237821

Table 7.

Effect of Tadalafil on Total IPSS and IPSS-QOL

Observation Period Measured Value Mean Change From Baseline
n Mean SD n Mean 95% CI
Total IPSS Baseline 1150 15.8 6.9
1M 861 12.5 6.5 818 −3.4 −3.8 to –3.1
3M 717 11.3 6.1 685 −4.5 −5.0 to –4.1
6M 701 11.2 6.3 663 −4.7 −5.1 to –4.2
12M 577 11.1 6.5 553 −4.7 −5.2 to –4.2
18M 485 11.0 6.2 467 −5.0 −5.6 to –4.4
LOCF 1063 11.5 6.8 988 −4.3 −4.7 to –3.9
IPSS-QOL Baseline 1149 4.2 1.1
1M 856 3.4 1.4 815 −0.9 −1.0 to –0.8
3M 718 3.0 1.3 686 −1.2 −1.3 to –1.1
6M 702 2.8 1.4 664 −1.4 −1.5 to –1.3
12M 580 2.8 1.3 554 −1.5 −1.6 to –1.3
18M 484 2.7 1.3 465 −1.5 −1.6 to –1.4
LOCF 1059 3.0 1.4 989 −1.3 −1.4 to –1.2

Abbreviations: CI, confidence interval; IPSS, International Prostate Symptom Score; LOCF, last observation carried forward; M, month(s); n, number of patients analyzed; QOL, quality of life; SD, standard deviation.