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(A) The scheme of preparation of PAE-SLNs by high-temperature emulsification–low-temperature curing combined with ultrasound. (B) Test scheme for gel strength. (C) Determination of in vitro mucoadhesion strength of gel by improved physical equilibrium method.
Abbreviations: PAE, paeonol; PAE-SLNs, paeonol-solid lipid nanoparticles; PAE-SLNs-ISG, paeonol-solid lipid nanoparticles-in situ gel.
