Table 2.
Metabolic Mechanisms of Paeonol
| Simulated Biological Samples | Model | k | t1/2 (h) | Regression Equation | R2 |
|---|---|---|---|---|---|
| Blank gastric juice | First order dynamics | 0.0470 | 14.74 ± 0.24 | y=−0.0470x+4.5913 | 0.99 |
| Artificial gastric juice | First order dynamics | 0.0609 | 10.49 ± 0.27 | y=−0.0609x+4.5669 | 0.97 |
| Blank intestinal juice | First order dynamics | 0.0104 | 66.63 ± 1.21 | y=−0.0104x+4.5977 | 0.93 |
| Artificial intestinal juice | First order dynamics | 0.0223 | 31.08± 0.32 | y=−0.0223x+4.5852 | 0.94 |
| Liver microsomes | First order dynamics | 0.0507 | 0.23 ± 0.03 | y=−0.0507x+4.5277 | 0.99 |