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. 2020 May 4;15:3137–3160. doi: 10.2147/IJN.S247935

Table 3.

Central Composite Design Experiments and Experimental Results

Runs Factor 1
A: DGG
(% w / v)
Factor 2
B: HPMC
(% w / v)
Factor 3
C: VG
(% w / v)
Response 1
Solution Viscosity
mPa
Response 2
Gel Viscosity
mPa
1 0.3345 0.1845 0.8170 27.40 ± 0.39 904.37 ± 10.49
2 0.5655 0.1845 0.8170 461.20 ± 3.25 1288.41 ± 9.41
3 0.3345 0.4155 0.8170 86.77 ± 0.82 1000.98 ± 11.49
4 0.5655 0.4155 0.8170 994.07 ± 7.12 1763.26 ± 21.44
5 0.3345 0.1845 1.6830 22.83 ± 0.11 902.25 ± 17.29
6 0.5655 0.1845 1.6830 362.30 ± 2.47 1795.40 ± 30.48
7 0.3345 0.4155 1.6830 126.37 ± 1.07 1453.09 ± 16.39
8 0.5655 0.4155 1.6830 822.00 ± 6.33 1955.85 ± 22.20
9 0.2500 0.3000 1.2500 73.07 ± 0.09 846.51 ± 13.84
10 0.6500 0.3000 1.2500 914.87 ± 5.59 1955.82 ± 19.22
11 0.4500 0.1000 1.2500 86.77 ± 0.11 1201.58 ± 23.04
12 0.4500 0.5000 1.2500 535.83 ± 2.37 1722.91 ± 21.89
13 0.4500 0.3000 0.5000 200.90 ± 0.92 1412.05 ± 13.90
14 0.4500 0.3000 2.0000 202.43 ± 1.20 1904.54 ± 26.77
15 0.4500 0.3000 1.2500 207.50 ± 0.42 1951.40 ± 20.16
16 0.4500 0.3000 1.2500 205.21 ± 1.38 1955.24 ± 18.53
17 0.4500 0.3000 1.2500 205.23 ± 1.22 1957.49 ± 19.36
18 0.4500 0.3000 1.2500 209.01 ± 2.03 1949.27 ± 20.66
19 0.4500 0.3000 1.2500 207.28 ± 0.91 1955.04 ± 18.30
20 0.4500 0.3000 1.2500 207.31 ± 0.62 1958.38 ± 25.01

Abbreviations: DGG, deacetylated gellan gum; HPMC, hydroxypropyl methylcellulose; VG, glycerin.