Table 2.
SNP-based genetic correlations (Rg) estimated by LDSC between the STARRS anxiety factor results (European sample, N=10,764) and related constructs from other samples.
PHENOTYPE | Rg | Standard Error | P-Value | N |
---|---|---|---|---|
ANGST Anxiety Factor Score (Otowa et al., 2016) | 0.891 | 0.659 | 0.176 | 18,186 |
Obsessive-Compulsive Disorder ((OCGAS), 2018) | 0.292 | 0.347 | 0.400 | 9,607 |
Major Depressive Disorder (Wray et al., 2018) | 0.507 | 0.336 | 0.132 | 173,005 |
Depressive Symptoms (Okbay et al., 2016) | 0.718 | 0.461 | 0.119 | 161,460 |
Neuroticism (GPC) (de Moor et al., 2015) | 0.851 | 0.622 | 0.172 | 63,661 |
Neuroticism (SSGAC) (Okbay et al., 2016) | 0.653 | 0.422 | 0.122 | 170,911 |
Schizophrenia (Consortium, 2014) | 0.115 | 0.16 | 0.719 | 150,064 |
Extraversion (GPC) (van den Berg et al., 2015) | −0.206 | 0.014 | 0.516 | 63,030 |
Loneliness (Gao et al., 2017) | 0.332 | 0.581 | 0.567 | 7,556 |
Subjective Well Being (SSGAC) (Okbay et al., 2016) | −0.922 | 0.707 | 0.192 | 298,420 |