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. 2020 May 8;3:225. doi: 10.1038/s42003-020-0960-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Photograph showing the position of the brainstem section on the electrode array; black represents stimulation sites, green and orange represent electrodes where the example excitatory and inhibitory responses (shown in c) were recorded. Black lines delineate structures: the AP and the borders of DVC. b Schematic representation of the stimulation protocol. c Representative excitatory and inhibitory responses in the NTS shown in modified peri-stimulus time histograms (PSTHs) representing the sum of spike density function around 30 stimuli. d Amplitudes of nocturnal excitations were significantly higher than those recorded during the day (*p = 0.042, Mann–Whitney test), but inhibitory responses did not show this day-to-night increase (p = 0.336, Mann Whitney test). e Proportion of excitations (in green) to inhibitions (in orange) recorded at day and night.