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. 2020 Apr;8(7):500. doi: 10.21037/atm.2020.03.130

Table 2. Subgroup analysis of AGREE-II scores for the guidelines of the five viruses (mean ± SD).

Categories SARS (n=21) MERS (n=9) EBOV (n=11) ZIKV (n=10) SARS-CoV-2 (n=30)
Publication year since outbreak
   ≤1 year 0.14±0.05 0.29±0.19 0.18±0.11
   >1 year 0.22±0.07 0.24±0.05 0.34±0.15
   t/F/H −3.195 0.459 −1.991
   P 0.005 0.660 0.078
Publication country/region
   International 0.19±0.00 0.23±0.08 0.32±0.17 0.38±0.18 0.22±0.08
   China 0.14±0.05 0.14±0.00 0.16±0.10 0.19±0.12
   America 0.22±0.03 0.14±0.00 0.24±0.03 0.16±0.05
   Others 0.31±0.06 0.38±0.18 0.27±0.15 0.13±0.00
   t/F/H 8.118 1.942 0.627 1.742 0.724
   P 0.001 0.224 0.620 0.137 0.547
Publication format
   Journal 0.17±0.08 0.32±0.23 0.35±0.20 0.24±0.01 0.44±0.00
   Website 0.23±0.10 0.24±0.08 0.23±0.11 0.36±0.18 0.18±0.08
   t/F/H −0.217 0.572 1.305 −1.698 3.307
   P 0.830 0.619 0.224 0.140 0.003
Organization
   WHO 0.19±0.00 0.23±0.08 0.26±0.11
   CDC 0.16±0.07 0.12±0.02
   Government 0.22±0.04 0.22±0.12 0.25±0.00
   Society/association 0.23±0.07 0.41±0.24 0.17±0.00
   Hospital 0.12±0.05
   University 0.59±0.00
   Not reported 0.12±0.03 0.4±0.00
   t/F/H 3.119 1.589 3.402 2.455* 14.367*
   P 0.040 0.279 0.103 0.29 0.006

All guidelines of Zika virus and SARS-CoV-2 were published in the same year, the data cannot carry out subgroup analysis for the publication year since outbreak. *, Kruskal-Wallis Test was used due to uneven variance; , publication year within an outbreak: 2003 (SARS-CoV), 2014 (Ebola virus), 2015 (MERS-CoV), 2016 (Zika virus), 2020 (SARS-CoV-2). SARS-CoV, Severe Acute Respiratory Syndrome coronavirus; EBOV, Ebola virus; MERS-CoV, Middle East Respiratory Syndrome coronavirus; ZIKV, Zika virus; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; CDC, Centers for Disease Control and Prevention of the United States; Chinese Center for Disease Control and Prevention; t, t value of Student’s t-test; F, F value of analysis of variance; H, H value of Kruskal-Wallis H test.