Table 2. Univariable Cox model of prognostic factors for PFS and OS.
| Factors | Univariate (PFS) | Univariate (OS) | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age, years | 1.216 | 0.999–1.479 | 0.051 | 1.179 | 0.906–1.534 | 0.222 | |
| Menopausal status | 1.228 | 1.006–1.498 | 0.043 | 1.294 | 0.993–1.687 | 0.056 | |
| FIGO stage [2009] | 2.185 | 1.791–2.666 | <0.001 | 2.407 | 1.839–3.151 | <0.001 | |
| Tumor diameter (cm) | 1.677 | 1.375–2.044 | <0.001 | 2.146 | 1.656–2.780 | <0.001 | |
| Depth of myometrial invasion | 3.136 | 2.362–4.164 | <0.001 | 5.993 | 3.658–9.819 | <0.001 | |
| LVSI | 2.939 | 2.403–3.594 | <0.001 | 3.762 | 2.843–4.979 | <0.001 | |
| Parametrial invasion | 3.767 | 2.886–4.917 | <0.001 | 4.644 | 3.324–6.487 | <0.001 | |
| Vaginal margin Invasion | 2.906 | 2.065–4.091 | <0.001 | 2.998 | 1.895–4.744 | <0.001 | |
| Adjuvant therapy | 1.693 | 1.351–2.120 | <0.001 | 1.891 | 1.387–2.579 | <0.001 | |
| pN stage | 3.356 | 2.772–4.062 | <0.001 | 3.721 | 2.880–4.808 | <0.001 | |
| 2018 FIGO stage | <0.001 | <0.001 | |||||
| 0 | Reference | Reference | |||||
| 1 | 3.016 | 2.466–3.688 | <0.001 | 3.317 | 2.533–4.345 | <0.001 | |
| 2 | 6.672 | 4.754–9.364 | <0.001 | 7.979 | 5.089–12.511 | <0.001 | |
| PLN | <0.001 | <0.001 | |||||
| 0 | Reference | Reference | |||||
| 1 | 2.685 | 2.171–3.320 | <0.001 | 2.751 | 2.058–3.678 | <0.001 | |
| 2 | 6.871 | 5.245–9.002 | <0.001 | 9.186 | 6.508–12.965 | <0.001 | |
| NLN | <0.001 | <0.001 | |||||
| 1 | Reference | Reference | |||||
| 2 | 0.285 | 0.185–0.441 | <0.001 | 0.262 | 0.148–0.464 | <0.001 | |
| 3 | 0.246 | 0.157–0.384 | <0.001 | 0.204 | 0.113–0.368 | <0.001 | |
| 4 | 0.262 | 0.171–0.402 | <0.001 | 0.223 | 0.127–0.392 | <0.001 | |
| LNR | <0.001 | <0.001 | |||||
| 0 | Reference | Reference | |||||
| 1 | 1.723 | 0.884–3.358 | 0.11 | 2.059 | 0.84–5.045 | 0.114 | |
| 2 | 2.682 | 2.129–3.379 | <0.001 | 2.632 | 1.916–3.614 | <0.001 | |
| 3 | 5.406 | 4.243–6.889 | <0.001 | 7.016 | 5.123–9.607 | <0.001 | |
| LODDS | <0.001 | <0.001 | |||||
| 1 | Reference | Reference | |||||
| 2 | 2.061 | 1.522–2.792 | <0.001 | 1.906 | 1.236–2.938 | 0.003 | |
| 3 | 2.7 | 1.988–3.665 | <0.001 | 2.874 | 1.913–4.320 | <0.001 | |
| 4 | 5.086 | 4.031–6.418 | <0.001 | 6.412 | 4.734–8.684 | <0.001 | |
PFS, progression-free survival; OS, overall survival; HR, hazard ratios; CI, confidence intervals; FIGO, Federation of Gynecology and Obstetrics; LVSI, lymph-vascular space invasion; PLN, positive lymph nodes; NLN, negative lymph nodes; LNR, lymph node ratio; LODDS, log odds of positive nodes.