Table 1. mPAP and WA/TA ratio changes in the rat CTEPH model.
Group | n | mPAP (mmHg) | WA/TA ratio (%) |
---|---|---|---|
NS control group | 20 | 13.73±1.54 | 32.94±2.75 |
Carrageenan control group | 20 | 15.92±1.13▲ | 35.39±7.30▲ |
PE group A | 20 | 25.51±1.37* | 76.41±5.97* |
PE group B | 20 | 29.82±1.26*# | 85.41±7.37*# |
Data are expressed as (mean ± SD). The WA/TA ratio gradually increased following repeated embolization in the PE group 3 weeks after the 3rd embolization (P<0.05), as indicated by mPAP, but no changes occurred in the control group (P>0.05). *, P<0.05, compared to control group; #, P<0.05, compared to PE group A; ▲, P>0.05, compared to the NS control group. WA/TA, wall area/total area; CTEPH, chronic thromboembolic pulmonary hypertension.