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. 2020 Apr;8(7):470. doi: 10.21037/atm.2020.03.113

Table S2. Clinical characteristics of patients in the training cohort and the external validation cohort.

Variables Training cohort (n=217) External validation cohort (n=122) P
Sex 0.010
   Male 144 97
   Female 73 25
Age, years 0.139
   <55 68 29
   ≥55 149 93
Surgery procedures 0.668
   Lobectomy 183 105
   Sublobectomy 34 17
TNM-stage <0.001
   IA 89 82
   IB 128 40
VPI 0.025
   No 150 98
   Yes 67 24
Smoking status 0.353
   No 109 56
   Yes 108 66
Histology 0.011
   Adeno 136 93
   Non-adeno 81 29
CA153, U/mL 0.740
   ≤25 198 110
   >25 19 12
CEA, U/mL 0.091
   ≤5 135 87
   >5 82 35
NSE, U/mL 0.948
   ≤12.5 188 106
   >12.5 29 16
Lymphocytes 0.798
Monocytes 0.426
Neutrophils <0.001
Platelets 0.406
White blood cells 0.465
LMR 0.050
   ≤3.6 178 89
   >3.6 39 33
NMR 0.004
   ≤4.9 127 91
   >4.9 90 31
NLR 0.016
   ≤3.0 134 91
   >3.0 83 31
PLR 0.083
   ≤154.0 201 106
   >154.0 16 16

CA153, carbohydrate antigen 153; CEA, carcinoembryonic antigen; NSE, neuron-specific enolase; LMR, lymphocyte-to-monocyte ratio; NLR, neutrocyte-to-lymphocyte ratio; NMR, neutrocyte-to-monocyte ratio; PLR, platelet-to-lymphocyte ratio.