Table S2. Clinical characteristics of patients in the training cohort and the external validation cohort.
Variables | Training cohort (n=217) | External validation cohort (n=122) | P |
---|---|---|---|
Sex | 0.010 | ||
Male | 144 | 97 | |
Female | 73 | 25 | |
Age, years | 0.139 | ||
<55 | 68 | 29 | |
≥55 | 149 | 93 | |
Surgery procedures | 0.668 | ||
Lobectomy | 183 | 105 | |
Sublobectomy | 34 | 17 | |
TNM-stage | <0.001 | ||
IA | 89 | 82 | |
IB | 128 | 40 | |
VPI | 0.025 | ||
No | 150 | 98 | |
Yes | 67 | 24 | |
Smoking status | 0.353 | ||
No | 109 | 56 | |
Yes | 108 | 66 | |
Histology | 0.011 | ||
Adeno | 136 | 93 | |
Non-adeno | 81 | 29 | |
CA153, U/mL | 0.740 | ||
≤25 | 198 | 110 | |
>25 | 19 | 12 | |
CEA, U/mL | 0.091 | ||
≤5 | 135 | 87 | |
>5 | 82 | 35 | |
NSE, U/mL | 0.948 | ||
≤12.5 | 188 | 106 | |
>12.5 | 29 | 16 | |
Lymphocytes | 0.798 | ||
Monocytes | 0.426 | ||
Neutrophils | <0.001 | ||
Platelets | 0.406 | ||
White blood cells | 0.465 | ||
LMR | 0.050 | ||
≤3.6 | 178 | 89 | |
>3.6 | 39 | 33 | |
NMR | 0.004 | ||
≤4.9 | 127 | 91 | |
>4.9 | 90 | 31 | |
NLR | 0.016 | ||
≤3.0 | 134 | 91 | |
>3.0 | 83 | 31 | |
PLR | 0.083 | ||
≤154.0 | 201 | 106 | |
>154.0 | 16 | 16 |
CA153, carbohydrate antigen 153; CEA, carcinoembryonic antigen; NSE, neuron-specific enolase; LMR, lymphocyte-to-monocyte ratio; NLR, neutrocyte-to-lymphocyte ratio; NMR, neutrocyte-to-monocyte ratio; PLR, platelet-to-lymphocyte ratio.