Table 1. Patient characteristics and clinical indicators.
| Index | Healthy control group (n=30) | Controlled asthma group (n=14) | Uncontrolled asthma group (n=35) |
|---|---|---|---|
| Age | 49.03±7.46 | 42.64±14.64 | 51.94±12.29 |
| Male sex (%) | 33.33 | 50.00 | 34.29 |
| BMI (kg/m2) | 22.57±2.95 | 21.10±3.76 | 22.56±3.02 |
| Smoking rate (%) | 10.00 | 28.57 | 40.00 |
| Allergic history (%) | 20.00 | 28.57 | 17.14 |
| Blood | |||
| Eosinophils (/mL) | 0.15±0.16×109/L | 0.34±0.34×109/L | 0.31±0.42×109/L |
| Neutrophils (/mL) | 3.60±1.16×109/L | 4.40±2.13×109/L | 5.75±3.01×109/L* |
| Sputum | – | ||
| Eosinophil (%) | 33.15±25.11 | 24.07±21.32 | |
| Neutrophil (%) | 47.18±34.02 | 61.25±24.19 | |
| FeNO (ppb) | – | 56.33±79.26 | 37.96±30.22 |
| Serum OLFM4 (pg/mL) | 1,830.11±1,239.70 | 3,450.38±3,000.35 | 5,084.57±3,425.76*# |
| Hs-CRP | – | 11.82±17.52 | 8.32±15.23 |
| FEV1% pred | – | 70.79±27.79 | 60.38±26.38 |
| Total IgE (IU/mL) | – | 211.67±204.94 | 414.15±512.44 |
Data are presented as means ± standard deviation. Data in the uncontrolled asthma group and the controlled asthma group were collected before inhaled corticosteroid (ICS) therapy. *, P<0.05 compared with the healthy control group; #, P<0.05 compared with the controlled asthma group; IgE, immunoglobulin E; OLFM4, olfactomedin 4; FEV1% pred, forced expiratory volume in one second as a percentage of predicted volume.