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. 2020 Apr;8(7):491. doi: 10.21037/atm.2020.03.47

Table 2. Closed pleural biopsy results, diagnosed as malignancy*.

Indicators Gold standard
Positive Negative Total
CPB
   Positive 135 0 135
   Negative 127 217 344
   Total 262 217 579
Test performance indicator
   Sensitivity (%)
      a/(a+c) =135/262 51.5%
   Specificity (%)
      d/(b+d) =217/217 100%
   Positive predictive value (%)
      a/(a+b) =135/135 100%
   Negative likelihood ratio (%)
      d/(c+d) =217/344 63.1%

*, malignancy included lung cancer, mesothelioma, hematological malignancy and metastatic carcinoma. a: true-positive results; b: false-positive results; c: false-negative results; d: true-negative results.