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. 2020 Apr;8(7):445. doi: 10.21037/atm.2020.03.145

Table 3. Effect of medium-term SHS exposure (yes vs. no) on outcomes in bivariate and multiple (adjusted) models.

Outcome variables Effect type Bivariate models Multiple models
Effect (95% CI) P value Effect (95% CI) P value
Patient-centred outcomes
   Chronic cough OR 2.55 (1.17–5.57) 0.02* 3.57 (1.22–10.40) 0.02*
   Chronic sputum OR 1.56 (0.69–3.52) 0.28 1.78 (0.54–5.85) 0.34
   Wheezing OR 1.99 (1.07–3.73) 0.03* 1.78 (0.72–4.40) 0.20
   Shortness of breath OR 1.94 (0.94–3.98) 0.07 1.56 (0.63–3.85) 0.33
   Fair or poor general health OR 2.24 (1.19–4.21) 0.01* 1.53 (0.61–3.85) 0.36
   Worse health in the past year OR 1.35 (0.60–3.08) 0.46 0.77 (0.28–2.06) 0.59
Disease-centred outcomes
   Outpatient visits ≥3 times per year OR 1.01 (0.54–1.88) 0.98 0.63 (0.31–1.29) 0.20
   Hospitalization ≥1 time per year OR 1.15 (0.40–3.35) 0.79 0.39 (0.09–1.72) 0.21
   Death during follow-up HR 1.21 (0.62–2.36) 0.56 0.72 (0.34–1.54) 0.39

Data obtained from the National Health and Nutrition Examination Survey (2007–2012), National Center for Health Statistics. , the reference category was the group without medium-term SHS exposure; , multiple models were adjusted by age, gender, ethnicity, family income-to-poverty ratio grading, GOLD grading, smoking history, inhaled bronchodilators, and inhaled combination of bronchodilators and corticosteroids; *, statistical significance at the P<0.05 level. CI, confidential interval; GOLD, Global Initiative for Chronic Obstructive Lung Disease; HR, hazard ratio; OR, odds ratio; SHS, secondhand smoke.