Figure 1.

Dezocine played concentration-related opposite roles on cell viability and migration in HepG2 and Hep 3B cells. Liver cancer Cells were incubated with Dezocine (0, 1, 2,4, 8 μg/mL) for 24 h. The cell viability was measured by CCK8 assay, cell migrate ability were measured by Wound healing and transwell assay. (A,B) Cell viability of HepG2 and Hep 3B cells in different concentrations of dezocine. (C,D,E,F) Cell migrate ability of HepG2 and Hep 3B cells in different concentrations of dezocine indicated by wound healing assay (scale bar: 200 µm). (G,H,I,J) Cell migrate ability of HepG2 and Hep 3B cells in different concentrations of dezocine indicated by transwell assay (cells were stained with crystal violet, scale bar: 200 µm). Data are represented as means ± SEM, n=3. *, P<0.05 vs. cells treated without dezocine; ^#P>0.1 vs. cells treated without dezocine.