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. 2020 Apr;8(7):480. doi: 10.21037/atm.2020.03.28

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Dezocine has diverse effects on aerobic glycolysis of liver cancer cells at different concentrations. (A) Dezocine treatment modified extracellular acidification rate (ECAR) of HepG2. (B) Cells glycolysis of HepG2 cells treated by dezocine. (C) Glycolysis capacity of HepG2 cells treated by dezocine. (D) Glycolysis reserve of HepG2 cells treated by dezocine. (E) Expression of HK2 and LDHA in HepG2 cells treated by dezocine. (F) Dezocine treatment modified ECAR of Hep 3B cells. (G) Cells glycolysis of Hep 3B cell treated by dezocine. (H) Glycolysis capacity of Hep 3B cell treated by dezocine. (I) Glycolysis reserve of Hep 3B cells treated by dezocine. (J) Expression of HK2 and LDHA in Hep 3B cells treated by dezocine. Data are represented as means ± SEM, n=3. *, P<0.05 vs. cells treated without dezocine; ^#P>0.1 vs. cells treated without dezocine.