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. 2020 Apr;8(7):459. doi: 10.21037/atm.2020.03.108

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Sam68 expression is positively correlated with PKM2 in CRC tissues. (A,B) Kaplan-Meier plots of overall survival versus Sam68 protein by IHC in CRC clinical samples from our tissue bank (×10, ×40). (C) The positive correlation between Sam68 protein and PKM2 mRNA expression in clinical CRC tissues. (D) Evaluation of the expression of Sam68 in CRC tissues and their paired normal tissues based on the data from the GDS2947 and TCGA databases. *P<0.05, ****P<0.0001. PKM2, pyruvate kinase muscle 2; CRC, colorectal cancer.