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. 2020 Apr;8(7):435. doi: 10.21037/atm.2020.03.204

Table 3. Association between sonographic features and TNBC molecular subtypes based on the FUSCC classification criteria.

Number IM LAR MES BLIS P
Orientation 0.529
  Parallel 100 20 (95.2) 15 (83.3) 30 (83.3) 35 (89.7)
  Not parallel 14 1 (4.8) 3 (16.7) 6 (16.7) 4 (10.3)
Shape 0.008*
  Regular 43 11 (52.4) 2 (11.1) 10 (27.8) 20 (51.3)
  Irregular 71 10 (47.6) 16 (88.9) 26 (72.2) 19 (48.7)
Margin 0.439
  Circumscribed 12 3 (14.3) 1 (5.6) 2 (5.6) 6 (15.4)
  Not circumscribed 102 18 (85.7) 17 (94.4) 34 (94.4) 33 (84.6)
Angular/spiculated margin 0.055
  Yes 38 6 (28.6) 10 (55.6) 14 (38.9) 8 (20.5)
  No 76 15 (71.4) 8 (44.4) 22 (61.1) 31 (79.5)
Echo pattern 0.180
  Hypoechoic 55 15 (71.4) 7 (38.9) 14 (38.9) 19 (48.7)
  Mixed 57 6 (28.6) 10 (55.6) 22 (61.1) 19 (48.7)
  Solid and cystic 2 0 (0) 1 (5.6) 0 (0) 1 (2.6)
Posterior acoustic pattern 0.028*
  Shadow 8 0 (0) 3 (16.7) 5 (13.9) 0 (0)
  Enhancement 43 9 (42.9) 4 (22.2) 9 (25) 21 (53.8)
  No change 53 10 (47.6) 11 (61.1) 17 (47.2) 15 (38.5)
  Mixed 10 2 (9.5) 0 (0) 5 (13.9) 3 (7.7)
Posterior acoustic shadow 0.021*
  Yes 8 0 (0) 3 (16.7) 5 (13.9) 0 (0)
  No 106 21 (100.0) 15 (83.3) 31 (86.1) 39 (100.0)
Posterior acoustic enhancement 0.031*
  Yes 43 9 (42.9) 4 (22.2) 9 (25) 21 (53.8)
  No 71 12 (57.1) 14 (77.8) 27 (75) 18 (46.2)
Calcification 0.549
  Yes 32 4 (19.0) 5 (27.8) 13 (36.1) 10 (25.6)
  No 82 17 (81.0) 13 (72.2) 23 (63.9) 29 (74.4)
US features-based groups 0.013*
  Group 1 31 7 (33.3) 2 (11.1) 8 (22.2) 14 (35.9)
  Group 2 66 14 (67.7) 10 (55.6) 19 (52.8) 23 (59.0)
  Group 3 17 0 (0) 6 (33.3) 9 (25.0) 2 (5.1)

* indicates statistical significance.