Table 3. Association between sonographic features and TNBC molecular subtypes based on the FUSCC classification criteria.
Number | IM | LAR | MES | BLIS | P | |
---|---|---|---|---|---|---|
Orientation | 0.529 | |||||
Parallel | 100 | 20 (95.2) | 15 (83.3) | 30 (83.3) | 35 (89.7) | |
Not parallel | 14 | 1 (4.8) | 3 (16.7) | 6 (16.7) | 4 (10.3) | |
Shape | 0.008* | |||||
Regular | 43 | 11 (52.4) | 2 (11.1) | 10 (27.8) | 20 (51.3) | |
Irregular | 71 | 10 (47.6) | 16 (88.9) | 26 (72.2) | 19 (48.7) | |
Margin | 0.439 | |||||
Circumscribed | 12 | 3 (14.3) | 1 (5.6) | 2 (5.6) | 6 (15.4) | |
Not circumscribed | 102 | 18 (85.7) | 17 (94.4) | 34 (94.4) | 33 (84.6) | |
Angular/spiculated margin | 0.055 | |||||
Yes | 38 | 6 (28.6) | 10 (55.6) | 14 (38.9) | 8 (20.5) | |
No | 76 | 15 (71.4) | 8 (44.4) | 22 (61.1) | 31 (79.5) | |
Echo pattern | 0.180 | |||||
Hypoechoic | 55 | 15 (71.4) | 7 (38.9) | 14 (38.9) | 19 (48.7) | |
Mixed | 57 | 6 (28.6) | 10 (55.6) | 22 (61.1) | 19 (48.7) | |
Solid and cystic | 2 | 0 (0) | 1 (5.6) | 0 (0) | 1 (2.6) | |
Posterior acoustic pattern | 0.028* | |||||
Shadow | 8 | 0 (0) | 3 (16.7) | 5 (13.9) | 0 (0) | |
Enhancement | 43 | 9 (42.9) | 4 (22.2) | 9 (25) | 21 (53.8) | |
No change | 53 | 10 (47.6) | 11 (61.1) | 17 (47.2) | 15 (38.5) | |
Mixed | 10 | 2 (9.5) | 0 (0) | 5 (13.9) | 3 (7.7) | |
Posterior acoustic shadow | 0.021* | |||||
Yes | 8 | 0 (0) | 3 (16.7) | 5 (13.9) | 0 (0) | |
No | 106 | 21 (100.0) | 15 (83.3) | 31 (86.1) | 39 (100.0) | |
Posterior acoustic enhancement | 0.031* | |||||
Yes | 43 | 9 (42.9) | 4 (22.2) | 9 (25) | 21 (53.8) | |
No | 71 | 12 (57.1) | 14 (77.8) | 27 (75) | 18 (46.2) | |
Calcification | 0.549 | |||||
Yes | 32 | 4 (19.0) | 5 (27.8) | 13 (36.1) | 10 (25.6) | |
No | 82 | 17 (81.0) | 13 (72.2) | 23 (63.9) | 29 (74.4) | |
US features-based groups | 0.013* | |||||
Group 1 | 31 | 7 (33.3) | 2 (11.1) | 8 (22.2) | 14 (35.9) | |
Group 2 | 66 | 14 (67.7) | 10 (55.6) | 19 (52.8) | 23 (59.0) | |
Group 3 | 17 | 0 (0) | 6 (33.3) | 9 (25.0) | 2 (5.1) |
* indicates statistical significance.