Table 1.
Patient preparation | |
Hydration |
Potential confounder Control by hydrating the patient whenever possible |
Data acquisition | |
Slice orientation |
Perpendicular to the vessel direction, prior to any bifurcations Good survey scan (e.g., angiography) needed |
TR, TE (ms) | Minimum to reduce acquisition time and flow-induced artifacts |
Flip angle (°) | Low to reduce acquisition time, but slightly higher than the optimal flip angle to increase inflow enhancement [(10–30) range] |
Velocity encoding (cm/s) |
Higher than the peak velocity to avoid aliasing Low enough not to compromise SNR (around 100) |
Spatial resolution |
Not too high-few pixels are enough Not too low to reliably identify vessels |
Motion compensation | Breath-hold or respiratory gating |
Cardiac gating |
Recommended for arterial flow measurements Either prospective or retrospective ECG |
Acquisition time | Below few minutes (to be compatible with multi-parametric MRI protocol) |
Image post-processing | |
Offset correction | Fit background plane to stationary regions (unless correction already integrated in the scanner) |
ROI definition |
Circular or elliptic, covering the lumen but not the vessel wall By manual, semi-automatic or automatic segmentation tools To be adjusted to account for movement of the vessels during the cardiac cycle |
Quality control |
Careful visual inspection Scan to be discarded in case of artifacts (even in few voxels of a single time frame) |