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. 2019 Aug 17;33(1):3–21. doi: 10.1007/s10334-019-00772-0

Table 5.

Phase-contrast MRI of the renal arteries: inter-study, intra-observer and inter-observer reproducibility

Study Methods Reproducibility results
King et al. [34] Repeated measurements Intra-observer: CV = 1.2% and 1.4%, ICC = 0.987 and 0.983; inter-observer: CV = 2.5%, reliability coefficient = 0.983
 19 ADPKD patients
Bax et al. [22] 3 repeated scans (2 successive + 7–21 days apart) Inter-study CV = 17% (successive scans) and 23% (longer time interval)
 19 HVs
Dambreville et al. [40] 6 repeated scans (2 successive + 4 ones 1-week apart) Inter-study RBF difference = 30.8 ± 3.5 mL/min (successive scans); CV = 10.6% (overall), CV = 9.0% (weekly interval), CV = 4.2% (successive scans)
 6 HVs
Wentland et al. [20] 2 repeated scans (n = 2) Inter-study RBF difference = 14.0 ± 12.5% (2D PC-MRI), 15.1 ± 15.6% (4D PC-MRI)
 10 HVs
Khatir et al. [15] 2 repeated scans (1–2 weeks apart) Inter-study CV = 8.3% (HVs) and 12.9% (CKD); ICC = 0.92 (HVs) and 0.78 (CKD)
 11 HVs and 9 CKD patients
Keegan et al. [12] 2 repeated scans + repeated measurements RBF difference: 38.5 ± 20.0 mL/min (inter-observer), 17.9 ± 44.8 (inter-study, observer 1), 24.2 ± 59.0 (inter-study, observe R2)
 10 HVs
Spithoven et al. [41] Repeated measurements Intra-observer: CV = 2.3%, ICC = 0.997 and 0.995; inter-observer: CV = 3.5%, ICC = 0.991
 21 ADPKD patients
Cox et al. [13] 2–3 repeated scans Inter-study CV = 14.4 ± 4.3%, ICC = 0.844
 11 HVs
Kline et al. [36] 2 repeated scans (24–210 h apart) Inter-study reproducibility: 10.1 ± 7.8%
 10 HVs

PC, phase contrast; ICC, intraclass correlation coefficient; RBF, renal blood flow; HVs, healthy volunteers; ADPKD, autosomal dominant polycystic kidney disease; CKD, chronic kidney disease; CV, coefficient of variation; CCC, concordance correlation coefficient