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. 2020 May 8;10:7759. doi: 10.1038/s41598-020-64805-8

Table 1.

Characteristics of the Study Patients with Leukaemia, Intracranial Malignancy and Lymphoma from the CICD and of the Comparison Controls from the LHID 2010.

Variables Leukaemia Control p value Intracranial malignancy Control p value Lymphoma Control p value
(n = 1423) (n = 14230) (n = 838) (n = 8380) (n = 272) (n = 2720)
n % n % n % n % n % n %
Gender 1.000 1.000 1.000
   Male 791 55.6 7910 55.6 479 57.2 4790 57.3 169 62.1 1690 62.1
   Female 632 44.4 6320 44.4 359 42.8 3590 42.7 103 37.9 1030 37.9
Age on index day* 1.000 1.000 1.000
   ≤6 1103 77.5 11030 77.5 542 64.7 5420 64.7 115 42.3 1150 42.3
   >6 320 22.5 3200 22.5 296 35.3 2960 35.3 157 57.7 1570 57.7
Urbanization level 1.000 1.000 1.000
   1 (city) 400 28.1 4000 28.1 217 25.9 2170 25.9 76 27.9 760 27.9
   2 701 49.3 7010 49.3 378 45.1 3780 45.1 120 44.1 1200 44.1
   3 207 14.6 2070 14.6 147 17.5 1470 17.5 40 14.7 400 14.7
   4 (villages) 115 8.1 1150 8.1 96 11.5 960 11.5 36 13.2 360 13.2
CT: one-year exclusion period 0.853 <0.001 0.247
   Yes 34 2.4 329 2.3 45 5.4 240 2.9 13 4.8 93 3.4
   No 1389 97.6 13901 97.7 793 94.6 8140 97.1 259 95.2 2627 96.6
CT: two-year exclusion period 0.494 0.031 0.860
   Yes 21 1.5 245 1.7 29 3.5 190 2.3 7 2.6 75 2.8
   No 1402 98.5 13985 98.3 809 96.5 8190 97.7 265 97.4 2645 97.2

Abbreviations: LHID = Longitudinal Health Insurance Database; CICD = Catastrophic Illness Certificate Database; CT = computed tomography.

*The index date was the disease diagnosis date in the disease group and the corresponding date in the non-diseased group.