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. 2020 May 8;11:2323. doi: 10.1038/s41467-020-16177-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a, b. Cell survival (determined by MTS assay) of C2C12 and PC12 cells in direct contact with various concentrations of tetracaine, P407 and P407-CM-T for 24 h (gray: 0.11 mg mL⁻¹; blue: 0.33 mg mL⁻¹; red: 1 mg mL⁻¹). c, d Cell survival (determined by MTS assay) of C2C12 and PC12 cells exposed to tetracaine (0.5% wt%), P407 (20% wt%) and P407-CM-T (20% wt%) in Transwells for 24 h (n = 3).* indicates p < 0.05 (unpaired t test) compared with untreated cells. Data are means ± SD. Source data are provided as a Source Data file.