Table 7.
Multivariate linear regression analysis of factors associated with physical component domains on quality of life questionnaires and pruritus status at 12 weeks.
| Physical functioning | Role-physical | Pruritus distribution, morning | Sleep disturbance, Frequency of scratching during sleep | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B (95% CI) | β | P | B (95% CI) | β | P | B (95% CI) | β | P | B (95% CI) | β | P | |
| Dialyzer type | 16.67 (3.44, 29.90) | 0.31 | 0.015 | 25.32 (3.43, 47.20) | 0.32 | 0.024 | −0.40 (−0.73, −0.06) | −0.34 | 0.022 | −0.92 (−1.57, −0.28) | −0.40 | 0.006 |
| Age | −0.17 (−0.68, 0.33) | −0.09 | 0.495 | −0.24 (−1.08, 0.59) | 0.56 | 0.560 | 0.01 (−0.01, 0.02) | 0.17 | 0.274 | −0.02 (−0.04, 0.01) | −0.21 | 0.173 |
| Gender | −3.79 (−20.30, 12.72) | −0.07 | 0.645 | 8.00 (−19.31, 35.30) | 0.56 | 0.557 | −0.25 (−0.66, 0.17) | −0.20 | 0.242 | −0.46 (−1.26, 0.35) | −0.19 | 0.256 |
| Diabetes | −14.33 (−27.81, −0.86) | −0.27 | 0.038 | −26.66 (−48.95, −4.38) | −0.34 | 0.020 | 0.07 (−0.27, 0.41) | 0.06 | 0.681 | −0.33 (−0.32, 0.99) | 0.14 | 0.313 |
| Hemoglobin | −2.44 (−10.08, 5.21) | −0.08 | 0.523 | −2.99 (−15.63, 9.66) | −0.07 | 0.636 | 0.15 (−0.05, 0.34) | 0.23 | 0.135 | 0.21 (−0.17, 0.58) | 0.16 | 0.269 |
| Albumin | 40.43 (15.58, 65.27) | 0.45 | 0.002 | 28.44 (−12.65, 69.53) | 0.21 | 0.170 | −0.32 (−0.95, 0.31) | −0.16 | 0.307 | −1.65 (−2.85, −0.44) | −0.42 | 0.009 |
| Total cholesterol | −0.09 (−0.35, 0.16) | −0.11 | 0.458 | −0.33 (−0.75, 0.09) | −0.27 | 0.088 | 0.003 (−0.003, 0.010) | 0.18 | 0.310 | 0.002 (−0.011, 0.014) | 0.04 | 0.805 |
Adjusted R-squared is 0.343 in the physical functioning domain, 0.186 in the role-physical domain, 0.100 for the morning pruritus distribution, and 0.178 for the frequency of scratching during sleep. The reference dialyzer is a high-flux dialyzer, and the reference gender is male.
Abbreviations: B, unstandardized regression coefficient; CI, confidence interval; β, standardized coefficient.