Table 1.
Baseline Characteristics of All 700 Patients
| Variable | No hepatic events (n = 651) | Hepatic events (n = 49) |
|---|---|---|
| Age | 46.9 ± 12.4 | 57 ± 9.5 |
| Male sex | 244 (38%) | 23 (47%) |
| BMI | 36.3 ± 7.3 | 35.8 ± 6.7 |
| Diabetes mellitus | 196 (30%) | 27 (55%) |
| HbgA1c | 6.6 ± 1.7 | 7.7 ± 2.1 |
| Serum sodium | 139.3 ± 5.2 | 139.1 ± 2.5 |
| Serum creatinine | 0.86 ± 0.2 | 1.0 ± 0.2 |
| WBC count | 8.0 ± 3.6 | 7.1 ± 2.4 |
| Neutrophil count | 5012 ± 2076 | 4084 ± 1777 |
| Lymphocyte count | 2162 ± 1212 | 1711 ± 749 |
| Neutrophil/lymphocyte ratio | 4.2 (1.7, 6.7) | 2.6 (2.2, 3.0) |
| Monocyte count | 521 ± 236 | 456 ± 183 |
| Platelet count | 263 (244–283) | 183 (164–201) |
| Total bilirubin | 0.50 (0.47–0.53) | 0.68 (0.58–0.77) |
| ALP | 92.0 (88.6–95.5) | 126.8 (64.5–189.0) |
| GGT | 87.3 (76.6–98.1) | 114 (79.8–144) |
| AST | 48.5 (44.5–54.6) | 61.1 (47.8–74.4) |
| ALT | 63.9 (59.7–68.2) | 71.4 (51.5–91.2) |
| Serum albumin | 4.4 (4.3–4.5) | 4.1 (4.0–4.2) |
| Prothrombin time | 10.9 ± 1.8 | 11.7 ± 3.2 |
| Serum transferrin | 25.8 (24.0–27.5) | 30.2 (24.0–36.5) |
| Serum ferritin | 219 (189–251) | 256 (135–378) |
| APRI Index | 0.63 (0.57–0.69) | 1.1 (0.89–1.4) |
| NAFLD fibrosis score | − 1.6 (− 1.8, − 1.3) | − 0.56 (− 1.3, − 0.17) |
BMI: body mass index; HgbA1c: hemoglobin A1c; WBC: white blood cell; ALP: alkaline phosphatase; GGT: gamma-glutamyl transferase: AST: aspartate aminotransferase; ALT: alanine aminotransferase; APRI: AST-to-platelet ratio index: NAFLD: non-alcoholic fatty liver disease