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. 2020 Apr 29;24:291–300. doi: 10.1016/j.jare.2020.04.020

Fig. 6.

Fig. 6

Lipid droplets are detectable in stromal cells of the medulla, (A) Lymph endothelial cells (LECs, Lyve1+), plasma cells, T cells and B cells as well as macrophages (M, CD11b+) are present in the medullary region of mLNs. mLNs were isolated 10 weeks after LFD (B, D) or HFD (C, E) feeding, fixed and stained with uranyl acetate and lead citrate. Representative pictures (1.8 kx) of the medulla and the medullary sinus are shown. Lymphocytes, plasma cells, and macrophages as mobile cells and sinusoidal reticulum cells, lymph endothelial cells, reticulum cells and FRCs as sessile cells were identified. Lipid droplets were detected in mLNs after HFD feeding. Abbreviations: FDC, follicular dendritic cell; FRC, fibroblastic reticulum cell; HEV, high endothelial venule; LD, lipid droplet; LEC, lymphatic endothelium cell; LP, lipophage; M, macrophage; MRC, marginal reticulum cell; PC, plasma cell; RC, reticulum cell; and SRC, sinusoidal reticulum cell.