Table 3.
Crude and adjusted linear regression coefficients and 95% confidence intervals for changes in LDL.
| Variable | Change in LDL | |||||
|---|---|---|---|---|---|---|
| Crude model | Simple interaction model | Fully adjusted model | ||||
| β | 95% CI | β | 95% CI | β | 95% CI | |
| Intercept | NA | NA | 0.159 | (-0.041, 0.349) | 0.804 | (-0.623, 2.232) |
| Atorvastatin use (yes) | Reference | Reference | Reference | Reference | Reference | Reference |
| Rosuvastatin use (yes) | 0.002 | (-0.113, 0.118) | -0.179 | (-0.449, 0.089) | -0.518 | (-0.902, -0.134) |
| Average exercise minutes/week (minutes) | -0.0004 | (-0.001, 0.001) | -0.001 | (-0.002, 0.001) | -0.002 | (-0.004, -0.001) |
| Rosuvastatin use∗ Average exercise interaction |
NA | NA | 0.001 | (-0.001, 0.003) | 0.004 | (0.001, 0.007) |
| Age (years) | 0.0001 | (-0.006, 0.006) | NA | NA | 0.005 | (-0.006, 0.015) |
| Sex (male) | 0.074 | (-0.043, 0.191) | NA | NA | 0.275 | (0.057, 0.493) |
| Tobacco smoking (previous/current smoker) | 0.004 | (-0.094, 0.101) | NA | NA | 0.003 | (-0.161, 0.167) |
| Other cholesterol-lowering medications (yes) | 0.033 | (-0.167, 0.233) | NA | NA | 0.099 | (-0.197, 0.396) |
| Anticoagulants (yes) | 0.031 | (-0.134, 0.197) | NA | NA | -0.205 | (-0.548, 0.138) |
| Antiplatelets (yes) | 0.099 | (-0.065, 0.264) | NA | NA | -0.124 | (-0.430, 0.182) |
| Cardiovascular medications (yes) | -0.033 | (-0.269, 0.204) | NA | NA | -0.079 | (-0.371, 0.214) |
| Oral antidiabetics (yes) | 0.005 | (-0.128, 0.138) | NA | NA | 0.049 | (-0.144, 0.241) |
| Insulin (yes) | -0.025 | (-0.275, 0.226) | NA | NA | -0.245 | (-0.599, 0.109) |
| Adherence (%) to exercise schedule (weekly sessions performed/prescribed) | -0.002 | (-0.005, 0.002) | NA | NA | 0.001 | (-0.005, 0.005) |
| Weight (kg) | 0.001 | (-0.002, 0.004) | NA | NA | -0.002 | (-0.007, 0.003) |
| Systolic BP (mmHg) | 0.001 | (-0.002, 0.005) | NA | NA | -0.005 | (-0.012, 0.002) |
| Diastolic BP (mmHg) | 0.004 | (-0.001, 0.010) | NA | NA | 0.008 | (-0.003, 0.018) |
| 6MWT at admission (meters) | -0.001 | (-0.001, 0.0001) | NA | NA | -0.001 | (-0.002, -0.0001) |
6MWT: 6-minute walk test; LDL: low-density lipoprotein; HDL: high-density lipoprotein; BP: blood pressure.