Table 6.
Crude and adjusted linear regression coefficients and 95% confidence intervals for changes in 6MWT.
| Variable | Change in 6MWT | |||||
|---|---|---|---|---|---|---|
| Crude model | Simple interaction model | Fully adjusted model | ||||
| β | 95% CI | β | 95% CI | β | 95% CI | |
| Intercept | NA | NA | 5.131 | (-24.940, 35.202) | 114.935 | (-19.333, 249.202) |
| Atorvastatin use (yes) | Reference | Reference | Reference | Reference | Reference | Reference |
| Rosuvastatin use (yes) | 36.440 | (18.090, 54.791) | 47.328 | (5.589, 89.067) | 46.021 | (2.866, 89.176) |
| Average exercise minutes/week (minutes) | -0.062 | (-0.225, 0.102) | 0.004 | (-0.204, 0.212) | -0.082 | (-0.297, 0.134) |
| Rosuvastatin use∗ Average exercise interaction |
NA | NA | -0.094 | (-0.408, 0.219) | -0.043 | (-0.363, 0.277) |
| Age (years) | -0.298 | (-1.243, 0.647) | NA | NA | -0.009 | (-1.067, 1.049) |
| Sex (male) | 9.749 | (-9.798, 29.295) | NA | NA | 14.808 | (-7.148, 36.763) |
| Tobacco smoking (previous/current smoker) | -1.037 | (-16.426, 14.352) | NA | NA | 1.571 | (-14.644, 17.787) |
| Other cholesterol-lowering medications (yes) | 5.982 | (-25.776, 37.741) | NA | NA | 9.326 | (-21.640, 40.293) |
| Anticoagulants (yes) | -3.371 | (-32.859, 26.118) | NA | NA | -7.992 | (-40.845, 24.860) |
| Antiplatelets (yes) | 12.388 | (-19.310, 44.086) | NA | NA | 16.740 | (-19.159, 52.640) |
| Cardiovascular medications (yes) | -14.115 | (-50.799, 22.569) | NA | NA | -9.581 | (-47.003, 27.842) |
| Oral antidiabetics (yes) | -31.361 | (-51.964, -10.757) | NA | NA | -25.519 | (-47.835, -3.203) |
| Insulin (yes) | -19.058 | (-53.710, 15.593) | NA | NA | -10.874 | (-45.502, 23.753) |
| Adherence (%) to exercise schedule (weekly sessions performed/prescribed) | -0.169 | (-0.682, 0.345) | NA | NA | -0.329 | (-0.865, 0.206) |
| Weight (kg) | -0.298 | (-0.769, 0.172) | NA | NA | -0.361 | (-0.906, 0.185) |
| Systolic BP (mmHg) | -0.128 | (-0.718, 0.462) | NA | NA | -0.512 | (-1.239, 0.214) |
| Diastolic BP (mmHg) | 0.240 | (-0.736, 1.216) | NA | NA | 0.143 | (-0.986, 1.272) |
6MWT: 6-minute walk test; BP: blood pressure.