Table 1. Significantly enriched GO terms and KEGG pathways of DEGs.
| Category | Term | Description | Count | FDR |
|---|---|---|---|---|
| BP | GO:0007067 | Mitotic nuclear division | 27 | 8.64E−15 |
| BP | GO:0051301 | Cell division | 28 | 4.98E−12 |
| BP | GO:0007062 | Sister chromatid cohesion | 15 | 1.60E−08 |
| BP | GO:0007059 | Chromosome segregation | 12 | 4.09E−07 |
| BP | GO:0000082 | G1/S transition of mitotic cell cycle | 12 | 3.40E−05 |
| BP | GO:0006260 | DNA replication | 11 | 0.01728675 |
| BP | GO:0008283 | Cell proliferation | 16 | 0.029764593 |
| BP | GO:0000086 | G2/M transition of mitotic cell cycle | 10 | 0.041628856 |
| CC | GO:0000777 | Condensed chromosome kinetochore | 14 | 9.87E−09 |
| CC | GO:0000775 | Chromosome, centromeric region | 11 | 5.29E−07 |
| CC | GO:0030496 | Midbody | 14 | 1.54E−06 |
| CC | GO:0000776 | Kinetochore | 10 | 2.51E−04 |
| CC | GO:0005819 | Spindle | 11 | 8.59E−04 |
| CC | GO:0005578 | Proteinaceous extracellular matrix | 15 | 0.00144238 |
| CC | GO:0005654 | Nucleoplasm | 55 | 0.006300472 |
| CC | GO:0005829 | Cytosol | 61 | 0.01409558 |
| MF | GO:0003777 | Microtubule motor activity | 10 | 2.36E−04 |
| KEGG | hsa04110 | Cell cycle | 12 | 1.59E−05 |
| KEGG | hsa04115 | p53 Signaling pathway | 7 | 0.037570687 |
Note:
BP, biological process; CC, cellular component; MF, molecular function; DEG, differentially expressed gene; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; FDR, adjust P value.