Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 21;52(4):672–681. doi: 10.1038/s12276-020-0424-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a The mRNA expression of p53 in the ELPC-treated ASCs. ***p < 0.001 compared to the control. n = 3. b The protein expression of p53 in the ELPC-treated ASCs. *p < 0.01, **p < 0.05 compared to the control. n = 3. c The ASCs treated with ELPC for 24 h were separated into the nuclear and cytosolic fractions. p53 was quantified and normalized to Lamin B2 and α-tubulin in the nucleus and cytosol, respectively. Cont Control, D DMSO-treated ASCs. *p < 0.01 **p < 0.05 ***p < 0.001 compared to the control. n = 3. d The translocation of p53 was confirmed by immunofluorescence staining. p53 was detected by FITC green fluorescence. The nucleus was stained with DAPI (blue). Scale bar: 30 μm. e, f The protein expression levels of Sox9 and Type II collagen in the ELPC-treated ASCs were investigated 24 h after transfection with 50 nM p53 siRNA. ***p < 0.001 compared to the control, ^#p < 0.05 compared to the ELPC-treated ASCs. ^$p < 0.001 compared to the reagent- and ELPC-treated ASCs. n = 3.