Table 2.
Genomic regions associated with immunoglobulin-resistance to GIN infection.
| Chra | Breed | Infection, parasite species | Association | Marker intervals (MI)/SNP/candidate gene (CG)/allelic effects | Reference |
|---|---|---|---|---|---|
| 0 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: s27388.1 | 78 |
| 1 | Churra | Strongylidae | IgA | OAR1 markers at position 37 cM (ILSTS044) | 106 |
| 1 | Spanish Churra | Natural, mainly T. circumcincta | IgA (L4) | MI: BMS835 - ILSTS044 | 77 |
| 3 | Soay | Natural, mainly T. circumcincta | IgA (L4) | CG: (o(IFN)-γ)*126 allele | 107 |
| 3 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | MI: KD103 - LYZ | 73 |
| 3 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: OAR3_227580261.1 | 78 |
| 3 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: OAR3_215619424.1 | 78 |
| 4 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: OAR4_90051359.1 | 78 |
| 4 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: OAR4_87762617.1 | 78 |
| 4 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: s57016.1 | 78 |
| 5 | Romane × Martinique Black Belly backcross | Artificial, H. contortus | IgG (ESP) | MI: OAR5_67605574.1–OAR5_67883800_X.1 | 81 |
| 5 | Romane × Martinique Black Belly backcross | Artificial, H. contortus | IgG (ESP) | MI: OAR5_100699982.1–DU183841_402.1 | 81 |
| 6 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: OAR6_107079726.1 | 78 |
| 8 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: OAR8_53084022.1 | 79 |
| 8 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: s42819.1 | 79 |
| 9 | Churra | Strongylidae | IgA | OAR9 markers at 50 cM position | 106 |
| 9 | Romane × Martinique Black Belly backcross | Artificial, H. contortus | IgG (ESP) | MI: OAR9_85325486.1–s48117.1 | 81 |
| 10 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: s56461.1 | 79 |
| 10 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: OAR10_23921485.1 | 79 |
| 10 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: s61799.1 | 79 |
| 11 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: DU232778_232.1 | 79 |
| 12 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: s68938.1 | 79 |
| 14 | Romane × Martinique Black Belly backcross | Artificial, H. contortus | IgG (ESP) | MI: OAR14_48832510.1–s30682.1 | 81 |
| 14 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: OAR14_21336208.1 | 79 |
| 15 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: s75729.1 | 79 |
| 20 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | MI: BM1815 - DRB1 | 73 |
| 20 | Rhönschaf | Artificial, H. contortus | IgL | DYMS1 (DYA) allele C | 71 |
| 20 | Scottish Blackface | Natural, mainly T. circumcincta | IgA (L3) | SNP: OAR20_40924783_X.1 | 78 |
| 21 | Romane × Martinique Black Belly backcross | Artificial, H. contortus | IgG (ESP) | MI: s27845.1–OAR21_14592163.1 | 81 |
| 23 | Romney × Coopworth | Natural, mainly T.colubriformis | IgE (total) | MI: Centomere - BM226 | 80 |
| 23 | Romney × Coopworth | Natural, mainly T.colubriformis | IgG (L3) | MI: McMA1 - ADCYCAP1 | 80 |
| 25 | Churra | Natural, mainly T. circumcincta | IgA (L4) | SNP: s21640.1 | 79 |
| 26 | Romane × Martinique Black Belly backcross | Artificial, H. contortus | IgG (ESP) | MI: OAR26_21857857.1–OAR26_22456940.1 | 81 |
aChromosome.