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. 2020 May 8;10:7787. doi: 10.1038/s41598-020-64759-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Volcano Plot. X-axis is the Log₂ of linear fold change (IPF/Controls) and Y-axis is the negative Log₁₀ of the Benjamini-Hochberg corrected t-test p value. Vertical red dashed lines denote a linear fold change of 2 in either direction (IPF/Controls or Controls/IPF). Horizontal red dashed line denotes a cutoff of 0.05 for the FDR corrected p value. Any protein which falls to the left or right of vertical red dashed lines and above horizontal red dashed line (p value <0.05) is deemed to be significant different between the groups.