Table 4.
Review of medical files of adult patients with Prader–Willi syndrome
| Country | Patient Files Reviewed (N) | Surgery with HC (N) | Surgery without HC (N) | Adrenal Crisis During Surgery (N) |
|---|---|---|---|---|
| Italy | 240 | 0 | 97 | 0 |
| UK | 42 | 0 | 13 | 0 |
| Sweden | 38 | 0 | 8 | 0 |
| Spain | 45 | 0 | 7 | 0 |
| France | 110 | 0 | 9 | 0 |
| Australia | 60 | 1 a | 13 | 0 |
| The Netherlands | 110 | 30 b | 53 c | 0 |
| Total | 645 | 31 | 200 | 0 |
Abbreviation: HC, hydrocortisone stress dose.
a The patient had been using daily hydrocortisone after an insufficient low-dose synacthen test. b 2 patients had been using daily hydrocortisone but were later tested sufficient; 28 had been using hydrocortisone during operation (16 of them were later tested sufficient). c 26 patients later tested sufficient (20 multiple-dose metyrapone test, 6 insulin tolerance test).