Table 4. DEX studies using chondrocytes isolated from arthritic patients and/or cultured with inflammatory cytokines.

Summary of cell source (OA: from patient with symptomatic OA), inflammatory cytokines used to model arthritic conditions, DEX concentration and duration of culture. N/A: not available. Wang et al. (2017b) Phosphoproteomics analysis of signaling changes in human chondrocytes following treatment with Il-1, IGF-1 and dexamethasone. Osteoarthritis Cartilage 25: S165–S166.

Authors	Year	Cell type	Cytokine treatment	DEX dose	Duration
Wang et al.	2017b	Human	10 ng/mL IL-1α	100 nM	30 min
Tu et al.	2013	Human, OA	N/A	63 μM	48 h
Stöve et al.	2002	Human, OA	0.1 ng/mL IL-1β	100 nM-10 μM	1 week
Palmer et al.	2002	Human, OA	10 ng/mL IL-1β or 100 ng/mL IL-6	100 nM	18 h
Shalom-Barak et al.	1998	Human	10 ng/mL IL-17	1–100 nM	48 h
Villiger et al.	1992	Human	10 ng/mL IL-1	100 nM	5 h
Roach et al.	2016	Bovine	10 ng/mL IL-1α	100 nM	35 d
Busschers et al.	2010	Equine	5 ng/mL IL-1β	100 nM-1 μM	24 h
Richardson and Dodge	2003	Horse	10 ng/mL IL-1β or 25 ng/mL TNFα	10 nM-1 μM	24 h
Sadowski and Steinmeyer	2001	Bovine	0.5 ng/mL IL-1α	100 nM–50 μM	48 h