Table 5. Results on cell viability and proliferation after DEX treatment on primary chondrocytes in non-arthritic model systems.
Authors | Year | Cell type | DEX dose | Duration | Effect on viability |
Shen et al. | 2015 | Human | 1 μM, 10 μM | 24 h | − |
Liu et al. | 2014 | Human | 100 μM | 72 h | − |
Stueber et al. | 2014 | Human | 10 μM–1 mM | 1 h | = |
Zaman et al. | 2014 | Human | 1 μM | 24–72 h | − |
Song et al. | 2012 | Human | 20–200 μM | 24 h-1 week | − |
Dragoo et al. | 2012 | Human | 1.5 mM | 1 week | = |
Authors | Year | Cell type | DEX dose | Duration | Effect on proliferation |
Mushtaq et al. | 2002 | Mouse | 10 nM–1 μM | 20 d | − |
Miyazaki et al. | 2000 | Rat | 0.1 nM–100 μM | 36 h | − |
Hainque et al. | 1987 | Rabbit | 10 nM–100 μM | 24 h-2 weeks | − |
Maor and Silbermann | 1986 | Mouse | 1 μM | 24 h | − |