Table 1.

Structural barriers encountered by physicians and staff enrolling cancer patients onto clinical trials (n = 120), September - November 2017.

	Total N = 120	Physicians N = 47	Staff N = 73	P value
	N (%)	N (%)	N (%)
Administrative
Paperwork is very complicated	55 (54.5)	26 (57.8)	29 (51.5)	0.55
Lack of support staff to assist with enrollment	47 (45.6)	24 (52.2)	23 (40.4)	0.23
Enrollment process is too time consuming	48 (49.0)	26 (56.5)	22 (42.3)	0.16
Difficult to keep track of the eligibility criteria	74 (73.3)	38 (84.4)	36 (64.3)	0.02
Patient-related
Patients frequently miss scheduled Appointments	35 (35.7)	14 (32.6)	21 (38.2)	0.56
Patients refuse placebo	43 (51.8)	20 (50.0)	23 (53.5)	0.75
Interacting with the patient’s family	30 (31.9)	8 (18.2)	22 (44.0)	0.007
Minority patients are difficult to enroll	28 (30.8)	12 (28.6)	16 (32.7)	0.67
Process-related
Very few eligible patients	45 (46.9)	22 (51.2)	23 (43.4)	0.45
Clinical trial protocols are too rigid	36 (35.0)	16 (34.8)	20 (35.1)	0.97
Too difficult to match patients to trials	24 (28.2)	13 (31.7)	11 (25.0)	0.49
Lack of minority physicians to recruit minority patients	40 (43.0)	20 (45.5)	20 (40.8)	0.65
Making time to discuss clinical trials with patients during office visits	47 (50.5)	31 (67.4)	16 (34.0)	0.001
Translating documents into Spanish and other languages is difficult and expensive	42 (44.7)	21 (48.8)	21 (41.2)	0.46
Communicating complex information to patients is very difficult	56 (57.1)	26 (56.5)	30 (57.7)	0.91
No space to enroll and consent patients	30 (30.6)	13 (28.3)	17 (32.7)	0.63
Heavy clinical patient volume	32 (35.6)	20 (44.4)	12 (26.7)	0.08