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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Alcohol Clin Exp Res. 2020 Mar 27;44(5):1025–1036. doi: 10.1111/acer.14318

Figure 4. HDID-1 mice exhibited a modest taste aversion to NaCl with a 2 g/kg dose of ethanol, but mifepristone did not enhance this aversive response.

Figure 4.

HDID-1 mice (n = 11–12/dose/condition/drug) were tested in an ethanol conditioned taste aversion task to see whether mifepristone administration would enhance the aversive effects of ethanol. Pairing of a 2 g/kg ethanol injection with the NaCl tastant produced a conditioned taste aversion, as evidenced by a main effect of condition on Day 20 that did not exist at baseline (Day 10). However, mifepristone did not moderate this effect. Data are shown separated by dose groups for ease of viewing. (* = p < 0.05; significant main effect of condition [ethanol vs. saline])