Figure 2.

Physiological changes and intestinal inflammation in mice induced with DSS. Body weights at different time points in (A) WT_Slit and Slit2-Tg mice and (B) WT_Robo1/2 and Robo1/2^+/- mice; Fecal consistency of the mice during the experiment; (C) WT_Slit and Slit2-Tg mice and (D) WT _Robo1/2 and Robo1/2^+/- mice; Feces were collected from the colon of individual mice immediately after sacrifice, and blood content was tested in fecal occult blood from (E) WT_Slit and Slit2-Tg mice and (F) WT_Robo1/2 and Robo1/2^+/- mice; Representative photographs of the colons at day 7 of DSS-induced and the statistic of colon lengths in (G) WT_Slit and Slit2-Tg mice and (H) WT_Robo1/2 and Robo1/2^+/- mice; n=10 in each group. Data are present as means ± SEM.