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. 2020 Apr 27;16(11):1972–1988. doi: 10.7150/ijbs.39259

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Silibinin treatment ameliorates fibrotic remodeling after myocardial I/R injury. A, Representative histological images and quantitative analysis of the Sirius Red staining in the infarct border zone and remote zone at 2 weeks after I/R (n=6 for each). B, Representative WB and quantitative analysis of α-SMA in reperfused myocardium (n=6 for each). C, Representative immunohistochemistry images and quantitative analysis of collagen-Ia1 and collagen-IIIa1 staining in the infarct border zone. D, CTGF and PAI-1 transcription levels determined by real-time PCR (n=6 for each). Bar=50 μm. *p<0.05 vs. Sham+vehicle. ^#p<0.05 vs. I/R+vehicle. NS, not significant.