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. 2020 Apr 27;16(11):1972–1988. doi: 10.7150/ijbs.39259

Figure 9.

Figure 9

Silibinin treatment prevents I/R-induced inflammatory response. A, Representative immunohistochemistry images of the MPO staining in the infarct border zone (black arrow). B, Quantitative analysis of MPO-positive cells infiltrated in reperfused myocardium at 24 hours after I/R (n=6 for each). C, Measurement of MPO activity in reperfused myocardium (n=6 for each). D, CXCL1, CXCL2, CXCL5 and CCL2 transcription levels determined by real-time PCR (n=6 for each). E, IL-6 and TNF-α transcription levels determined by real-time PCR in the border zone (n=6 for each). F, Transcription level of NLRP3 determined by real-time PCR in the border zone (n=6 for each). G, the levels of IL-6 and TNF-α in the plasma after myocardial I/R injury. Bar=50 μm. *p<0.05 vs. Sham+vehicle. #p<0.05 vs. I/R+vehicle. NS, not significant.