Fig. 4.

The ability of compound 22 to induce cytotoxicity in (a) non-melanoma (A431) cells and (b) non-malignant keratinocyte (HaCaT) cells. Cells were exposed to100 μM of compound 22 for 24, 48 and 72 h. Data shown are means ± SD of 5 replicates from three independent experiments. Asterisk (*), hashtag (#) or rhombus (◊) denote statistical significance when compared to their respective controls at p < 0.05. **, ## and ◊◊ denote statistical significance at p < 0.01 whereas ***, ###, ◊◊◊ at p < 0.001