Table 2.
Cox regression analysis of follow-up data of breast cancer patients in Northwest of Iran, between 2007 and 2016.
| Variable | Univariate Cox regression | Multivariate Cox regression∗ | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Freq. (percent) | HR† | 95% CI | p value | HR∗ | 95% CI | p value | ||||
| Age | <50 | 658 (49.3) | Ref. | — | — | — | Ref. | — | — | — |
| ≥50 | 677 (50.7) | 1.26 | 0.98 | 1.61 | 0.070 | 1.28 | 1.00 | 1.64 | 0.050 | |
|
| ||||||||||
| Sex | Female | 1309 (98.1) | Ref. | — | — | — | Ref. | — | — | — |
| Male | 26 (1.9) | 1.42 | 0.70 | 2.88 | 0.325 | 1.34 | 0.66 | 2.73 | 0.414 | |
|
| ||||||||||
| Grade | I | 232 (17.4) | Ref. | — | — | — | Ref. | — | — | |
| II | 511 (38.3) | 1.52 | 0.98 | 2.34 | 0.059 | 1.55 | 1.00 | 2.40 | 0.048 | |
| III | 86 (6.4) | 2.53 | 1.47 | 4.36 | 0.001 | 2.57 | 1.49 | 4.44 | 0.001 | |
| Unknown | 506 (37.9) | 1.93 | 1.28 | 2.91 | 0.002 | 1.98 | 1.27 | 3.07 | 0.002 | |
| 0.001∗∗ | ||||||||||
|
| ||||||||||
| Morphology | DC | 1036 (77.6) | Ref. | — | — | — | Ref. | — | — | — |
| LC | 81 (6.1) | 0.86 | 0.50 | 1.49 | 0.598 | 0.73 | 0.42 | 1.306 | 0.288 | |
| Others | 73 (5.5) | 0.86 | 0.54 | 1.37 | 0.522 | 0.70 | 0.43 | 1.15 | 0.163 | |
| NOS | 145 (10.9) | 1.63 | 1.16 | 2.29 | 0.005 | 1.36 | 0.92 | 1.99 | 0.119 | |
| 0.032∗∗ | 0.001∗∗ | |||||||||
†Unadjusted Hazard Ratio; ∗Adjusted Hazard Ratio; ∗∗Total p Value. HR: hazard ratio; CI: confidence interval.