Table 1.
HWE was assayed using the freely available resource at https://ihg.gsf.de/cgi-bin/hw/hwa2.pl from the University of Munich. P values were calculated using Pearson’s goodness-of-fit chi-square with one degree of freedom
| Disease | Subjects | Ins/Ins | Ins/Del | Del/Del | MAF | HWE | Country | Reference |
|---|---|---|---|---|---|---|---|---|
| P value | ||||||||
| T2DM | Controls | 94 | 3 | 1 | 0.03 | 1.42×10-4 | Turkey | (6) |
| Cases | 74 | 14 | 12 | 0.19 | 4.99×10-8 | |||
| Parkinson’s disease | Controls | 95 | 21 | 2 | 0.11 | 0.511 | Greece | (9) |
| Cases | 156 | 52 | 7 | 0.15 | 0.309 | |||
| VIH susceptibility | Controls | 189 | 65 | 3 | 0.14 | 0.318 | Spain | (7) |
| Cases | 160 | 18 | 0 | 0.05 | 0.477 | |||
| General population | Controls | 208 | 85 | 11 | 0.18 | 0.531 | Poland | (10) |
| Gastric cancer | Controls | 75 | 65 | 8 | 0.27 | 0.202 | Japan | (11) |
| Cases | 126 | 112 | 51 | 0.37 | 4.1×10-3 | |||
| Alzheimer’s disease | Controls | 172 | 168 | 60 | 0.36 | 0.077 | China | (12) |
| Cases | 150 | 161 | 89 | 0.42 | 4.37×10-4 | |||