Fig.1.

Indications of PGS in IVF patients referred to Royan Institute and its influence on the pregnancy rate. A. 213 patients were chosen to undergo PGS by aCGH for several reasons including ART failure (41.3%), recurrent miscarriage (RM, 39.4%) and chromosomal abnormality of parents (8.5%). Some patients who had heterogeneous characteristics (such as advanced age and unexplained infertility) were classified as “others” comprising 10.8% of the population. B. Regardless of the indications of PGS, pregnancy success rate was calculated for IVF and reported as pregnancy rate per ET and cycle. C. Pregnancy rate (per ET and cycle) for patients with ART failure and RM. D. Evaluating the effect of age on IVF success rate, presented as pregnancy rate per ET and cycle for ART failure and RM groups. PGS; Preimplantation genetic screening, IVF; In vitro fertilization, aCGH; Array comparative genomic hybridization, ART; Assisted reproductive technology, and ET; Embryo transfer. Patients are categorized by their ages: Ages>35 years ≤35.