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Effect of arbutin on the t-BHP-induced cytotoxicity in fibroblast cells. Arbutin pre-treatment inhibited necrosis of human fibroblast cells in a dosedependent manner after A-E. 24 hours and F-J. 48 hours exposure to t-BHP. The necrosis rate of cells cultured in the A, F. Control, B, G. 30 μM tert-butyl hydroperoxide, C, H. 50 μM arbutin+30 μM t-BHP, D, I. 250 μM arbutin+30 μM t-BHP, and E, J. 1000 μM arbutin+30 μM t-BHP
