Table 2.
HOMA-IR, RBC Folate, and Homocysteine Concentrations by Genotype
| Variables | CC | CT | TT | P |
|---|---|---|---|---|
| RBC folate (nmol/L)a | ||||
| GDM | 717.1 (233.0) | 667.2 (238.4) | 895.9 (291.7) | 0.016 |
| Non-GDM | 596.2 (195.2) | 645.7 (220.3) | 816.3 (297.5) | <0.001 |
| All | 611.5 (202.4) | 649.8 (223.3) | 832.9 (296.8) | <0.001 |
| Homocysteine (μmol/L)b | ||||
| GDM | 8.6 (1.3) | 9.0 (1.6) | 9.2 (2.4) | 0.688 |
| Non-GDM | 8.7 (1.4) | 8.6 (1.2) | 10.0 (4.5) | 0.002 |
| All | 8.7 (1.3) | 8.7 (1.3) | 9.8 (4.2) | 0.001 |
| HOMA-IRc | ||||
| GDM | 1.91 (0.96–4.66) | 2.23 (1.45–2.84) | 1.89 (1.38–3.31) | 0.866 |
| Non-GDM | 1.66 (1.15–2.24) | 1.29 (0.93–1.92) | 1.47 (1.05–2.07) | 0.077 |
| All | 1.66 (1.13–2.45) | 1.42 (0.98–2.31) | 1.53 (1.10–2.26) | 0.347 |
Notes: a,bAdjusted for age, BMI, and use of FA supplements. cComparisons made using the Kruskal–Wallis H-test.