Table 3.
Association of GDM Risk with RBC Folate Levels
| RBC Folate levels | GDM, n (%) | Model Onea | Model Twob | ||
|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||
| Q1(<509.0nmol/L) | 12 (13.2) | 1.00 (Reference) | – | 1.00 (Reference) | – |
| Q2 (509.0–647.9nmol/L) | 15(16.3) | 1.417 (0.612–3.277) | 0.416 | 1.354 (0.530–3.456) | 0.526 |
| Q3 (648.0–862.4nmol/L) | 17(18.7) | 1.671 (0.735–3.800) | 0.173 | 1.374 (0.546–3.455) | 0.500 |
| Q4 (≥862.5nmol/L) | 24(26.1) | 2.567 (1.173–5.619) | 0.018 | 2.473 (1.013–6.037) | 0.047 |
| As a continuous variable (SD, 262.4 nmol/L) | – | 1.001 (1.000–1.002) | 0.071 | 1.001 (1.000–1.002) | 0.121 |
Notes: aWithout adjustment for covariates. bAdjusted for age, physical activity, BMI, parity, family history of diabetes, use of folic acid supplements, HOMA-IR, C-reactive protein, hemoglobin, vitamin B12, and serum homocysteine.