. 2020 May 5;13:333–344. doi: 10.2147/CCID.S248280

Table 2.

Sinclair Pharmaceuticals Products for Minimally Invasive Rejuvenation

	PCL Collagen Stimulator^a	PLLA/PLGA Suspension Suture^b	Cross-Linked HA^c
Concept	Dermal filler stimulating collagen production	3D cone-based suspension suture	Cross-linked resorbable high molecular weight HA gel
Indications	Volume restoration Facial reshaping Skin quality improvement	Facial and neck contour reshaping Tissue repositioning Collagen stimulation	Wrinkle correction Volume restoration Facial contouring
Product range	3 Products ≥18 Months 24 Months 36 Months Duration of effect^d	3 Products 8 Cones 12 Cones 16 Cones	5 Products BDDE cross-linked HA gels (20 mg/mL) Variable particle sizes

PCL Collagen Stimulator^a

PLLA/PLGA Suspension Suture^b

Cross-Linked HA^c

Concept

Dermal filler stimulating collagen production

3D cone-based suspension suture

Cross-linked resorbable high molecular weight HA gel

Indications

Volume restoration
Facial reshaping
Skin quality improvement

Facial and neck contour reshaping
Tissue repositioning
Collagen stimulation

Wrinkle correction
Volume restoration
Facial contouring

Product range

3 Products

≥18 Months
24 Months

36 Months

Duration of effect^d

3 Products

8 Cones
12 Cones
16 Cones

5 Products

BDDE cross-linked HA gels (20 mg/mL)

Variable particle sizes

Notes: ^aEllansé^®; ^bSilhouette Soft^®; ^cPerfectha^®; ^dExpected longevity in vivo based on extrapolation of clinical data from S and M versions and accepted PCL degradation behavior.

Abbreviations: BDDE, butanediol diglycidyl ether; HA, hyaluronic acid; PCL, polycaprolactone; PLLA/PLGA, poly-L-lactic acid/poly-glycolic acid.