Table 5.
Comparison of Mean Macular and RNFL Thickness During Third Trimester in GDM, Healthy Pregnant Women and Healthy Non-Pregnant Women in Previously Published Studies
| Present Study, 2020 | Acmaz et al, 20157 | Sasikumar et al, 20188 | ||||||
|---|---|---|---|---|---|---|---|---|
| Country | Malaysia | Turkey | India | |||||
| Population (Number) | GDM Women | Pregnant Women | Non-Pregnant Women | GDM Women | Pregnant Women | Non-Pregnant Women | GDM Women | Pregnant Women |
| Number of patients | 78 | 72 | 70 | 72 | 48 | 76 | 176 | 188 |
| Gestational weeks | 28–38 weeks | NA | NA | 24–40 weeks | NA | 32–34 weeks | ||
| Age (years), mean (SD) | 33.18 (5.68) | 31.57 (4.90) | 32.47 (8.25) | 32.51 (4.88) | 27.72 (5.12) | 31.87 (7.76) | 28 (NA) | 28 (NA) |
| Macular thickness (µm), mean (SD) | 236.08 (16.44) | 237.26 (22.42) | 240.66 (20.95) | 252.53 (18.70) | 255.58 (17.54) | 265.09 (21.67) | NA | NA |
| RNFL thickness, (µm), mean (SD) | 97.27 (9.14) | 99.83 (12.44) | 97.97 (10.07) | 101.93 (8.72) | 104.45 (10.06) | 99.59 (12.02) | 91.16 (13.25) | 100.75 (41.55) |
| Instrument | Cirrus HD-OCT | Heidelberg Spectralis OCT | Cirrus HD-OCT | |||||
Abbreviations: RNFL, retinal nerve fibre layer; GDM, gestational diabetes mellitus; SD, standard deviation; OCT, optical coherence tomography; NA, not available.