Table 1.

Baseline Characteristics of Adults Diagnosed with Primary ITP, 2011–2016

Variable	N	%
Total	447	100
Age, years
18–39	92	20.6
40–49	73	16.3
50–64	138	30.9
65+	144	32.2
Male sex	212	47.4
Race
White	273	61.1
Black	47	10.5
Asian	10	2.2
Other	36	8.1
Comorbidities
Diabetes	118	26.4
Myocardial infarction	41	9.2
COPD and/or asthma	100	22.4
Coronary artery disease or atherosclerosis	107	23.9
Cerebrovascular disease	88	19.7
Congestive heart failure	57	12.8
Liver disease	49	11.0
Pulmonary embolism	6	1.3
Deep vein thrombosis	5	1.1
Any bleeding event	232	51.9
Intracranial hemorrhage	7	1.6
Gastrointestinal hemorrhage	66	14.8
Hematuria	49	11
Ecchymosis	43	9.6
Epistaxis	19	4.3
Previous ITP Therapies
Any rescue therapya	187	41.8
IV anti-D	4	0.9
IVIg	21	4.7
IV steroids	159	35.6
Platelet transfusion	25	5.6
Oral corticosteroids	240	53.7
Rituximab	7	1.6
Splenectomy	2	0.4
Number of Non-Rescue Therapiesb
0	205	45.9
1	231	51.7
2	9	2
3	2	0.4
4+	0	0
Platelet Measurements
Lowest platelet count in 60 days prior to diagnosis, (109/L)
Median (IQR)	85	(38.8, 125.0)
Missing	103	23

Notes: ^aAny rescue therapy included IV anti-D; IVIg; IV steroids; platelet transfusion. ^bThere were no administrations of danazol, mycophenolate mofetil, vinca alkaloids (vincristine or vinblastine), or alemtuzumab. Less than 1% had a prior administration of azathioprine, cyclosporine A, cyclophosphamide, or dapsone.

Abbreviations: Anti-D, Rho(D) immune globulin; COPD, chronic obstructive pulmonary disease; IQR, interquartile range; ITP, immune thrombocytopenia; IV, intravenous; IVIg, intravenous immunoglobulin.