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. 2020 May 5;14:1717–1727. doi: 10.2147/DDDT.S244516

Figure 3.

Figure 3

Effects of actinin alpha 1 (ACTN1) knockdown on cell migration, invasion, and epithelial-mesenchymal transition (EMT) in vitro. ACTN1 cells that were stably knocked down were named shACTN1, and negative control cells were named NC. The migration and invasion capabilities of the shACTN1 and NC group cells were evaluated by transwell (A, B) and wound-healing (C,D) assays. E-cadherin and vimentin protein levels in the shACTN1 and NC group cells were detected by Western blotting (E). For panel A and C, the left side shows representative images, and the right side shows statistical results. *P <0.05.