Fig. 3.

Representative cellular and developmental defects. Representative tissue-specific LOF of young essential genes leading to (A) defects in notum scutellar morphologies, (B) irregular bristle patterning and loss of bristles, (C) necrosis and tissue death at multiple places in the notum, (D) tumor formation at the junction between scutum and scutellum, (E) loss of asymmetric patterning with mirror-like wings and ectopic bristles, and (F) possible signaling defect with wing notches. Genotypes of flies are shown above each image, with scale bars in the lower right corners. Yellow arrowheads point to particular phenotypic defects.